NURS 6501 Week 2 Assignment: An understanding of cells and cell behavior is a critically important component of disease diagnosis and treatment. But some diseases can be complex in nature, with a variety of factors and circumstances impacting their emergence and severity

NURS 6501 Week 2 Assignment: An understanding of cells and cell behavior is a critically important component of disease diagnosis and treatment. But some diseases can be complex in nature, with a variety of factors and circumstances impacting their emergence and severity

NURS 6501 Week 2 Assignment: An understanding of cells and cell behavior is a critically important component of disease diagnosis and treatment. But some diseases can be complex in nature, with a variety of factors and circumstances impacting their emergence and severity

An understanding of cells and cell behavior is a critically important component of disease diagnosis and treatment. But some diseases can be complex in nature, with a variety of factors and circumstances impacting their emergence and severity.
Effective disease analysis often requires an understanding that goes beyond isolated cell behavior. Genes, the environments in which cell processes operate, the impact of patient characteristics, and racial and ethnic variables all can have an important impact.

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An understanding of the signals and symptoms of alterations in cellular processes is a critical step in the diagnosis and treatment of many diseases. For APRNs, this understanding can also help educate patients and guide them through their treatment plans.
In this Assignment, you examine a case study and analyze the symptoms presented. You identify cell, gene, and/or process elements that may be factors in the diagnosis, and you explain the implications to patient health.
RESOURCES

Be sure to review the Learning Resources before completing this activity.
Click the weekly resources link to access the resources.
WEEKLY RESOURCES
To prepare:
By Day 1 of this week, you will be assigned to a specific case study for this Case Study Assignment. Please see the “Announcements” section of the classroom for your assignment from your Instructor.
The Assignment Week 2 Case Study
DR. Bosede Omolola Adedire
.
Scenario: A 65-year-old obese African American male patient presents to his HCP with crampy left lower quadrant pain, constipation, and fevers to 101˚ F. He has had multiple episodes like this one over the past 15 years and they always responded to bowel rest and oral antibiotics. He has refused to have the recommended colonoscopy even with his history of chronic inflammatory bowel disease (diverticulitis), sedentary lifestyle, and diet lacking in fiber. His paternal grandfather died of colon cancer back in the 1950s as well. He finally underwent colonoscopy after his acute diverticulitis resolved. Colonoscopy revealed multiple polyps that were retrieved, and the pathology was positive for adenocarcinoma of the colon.
To prepare:
The Assignment
Develop a 1- to 2-page case study analysis in which you:
• Explain why you think the patient presented the symptoms described.
• Identify the genes that may be associated with the development of the disease.
• Explain the process of immunosuppression and the effect it has on body systems.
• Refer to the rubric for information required within your paper.
• Next, cl McCance, K. L. & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier.
o Chapter 7: Innate Immunity: Inflammation and Wound Healing
o Chapter 8: Adaptive Immunity (stop at Generation of clonal diversity); Summary Review
o Chapter 9: Alterations in Immunity and Inflammation (stop at Deficiencies in immunity); Summary Review
o Chapter 10: Infection (stop at Infectious parasites and protozoans); (start at HIV); Summary Review
o Chapter 11: Stress and Disease (stop at Stress, illness & coping); Summary Review

o Chapter 12: Cancer Biology (stop at Resistance to destruction); Summary Review
o Chapter 13: Cancer Epidemiology (stop at Environmental-Lifestyle factors); Summary Review
• Justiz-Vaillant, A. A., & Zito, P. M. (2019). Immediate hypersensitivity reactionsLinks to an external site.. In StatPearls. Treasure Island, FL: StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK513315/
Credit Line: Immediate Hypersensitivity Reactions – StatPearls – NCBI Bookshelf. (2019, June 18). Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK513315/. Used with permission of Stat Pearls.
Note: This article was presented in the Week 1 resources. If you read it previously you are encouraged to review it this week

NURS_6501_Module1_Case Study Assignment Rubric
Criteria Ratings Pts
This criterion is linked to a Learning Outcome Develop a 1- to 2-page case study analysis, examining the patient symptoms presented in the case study. Be sure to address the following: Explain why you think the patient presented the symptoms described. 30 to >27.0 pts
Excellent
The response accurately and thoroughly describes the patient symptoms. … The response includes accurate, clear, and detailed reasons, with explanation for the symptoms supported by evidence and/or research, as appropriate, to support the explanation. 27 to >24.0 pts
Good
The response describes the patient symptoms. … The response includes accurate reasons, with explanation for the symptoms supported by evidence and/or research, as appropriate, to support the explanation. 24 to >22.0 pts
Fair
The response describes the patient symptoms in a manner that is vague or inaccurate. … The response includes reasons for the symptoms, with explanations that are vague or based on inappropriate evidence/research. 22 to >0 pts
Poor
The response describes the patient symptoms in a manner that is vague and inaccurate, or the description is missing. … The response does not include reasons for the symptoms, or the explanations are vague or based on inappropriate or no evidence/research.
30 pts
This criterion is linked to a Learning Outcome Identify the genes that may be associated with the development of the disease. 25 to >22.0 pts
Excellent
The response includes an accurate, complete, detailed, and specific analysis of the genes that may be associated with the development of the disease. 22 to >19.0 pts
Good
The response includes an accurate analysis of the genes that may be associated with the development of the disease. 19 to >17.0 pts
Fair
The response includes a vague or inaccurate analysis of the genes that may be associated with the development of the disease. 17 to >0 pts
Poor
The response includes a vague or inaccurate analysis of the genes that may be associated with the development of the disease is missing.
25 pts
This criterion is linked to a Learning Outcome Explain the process of immunosuppression and the effect it has on body systems. 30 to >27.0 pts
Excellent
The response includes an accurate, complete, detailed, and specific explanation of the process of immunosuppression and the effect it has on body systems. 27 to >24.0 pts
Good
The response includes an accurate explanation of the process of immunosuppression and the effect it has on body systems. 24 to >17.0 pts
Fair
The response includes a vague or inaccurate explanation of the process of immunosuppression and the effect it has on body systems. 17 to >0 pts
Poor
The response includes a vague or inaccurate explanation of the process of immunosuppression and the effect it has on body systems.
30 pts
This criterion is linked to a Learning Outcome Written Expression and Formatting – Paragraph Development and Organization: Paragraphs make clear points that support well-developed ideas, flow logically, and demonstrate continuity of ideas. Sentences are carefully focused—neither long and rambling nor short and lacking substance. A clear and comprehensive purpose statement and introduction are provided that delineate all required criteria. 5 to >4.0 pts
Excellent
Paragraphs and sentences follow writing standards for flow, continuity, and clarity. … A clear and comprehensive purpose statement, introduction, and conclusion are provided that delineate all required criteria. 4 to >3.0 pts
Good
Paragraphs and sentences follow writing standards for flow, continuity, and clarity 80% of the time. … Purpose, introduction, and conclusion of the assignment are stated, yet are brief and not descriptive. 3 to >2.0 pts
Fair
Paragraphs and sentences follow writing standards for flow, continuity, and clarity 60%–79% of the time. … Purpose, introduction, and conclusion of the assignment are vague or off topic. 2 to >0 pts
Poor
Paragraphs and sentences follow writing standards for flow, continuity, and clarity < 60% of the time. … No purpose statement, introduction, or conclusion were provided.
5 pts